Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling

The study investigates the potential of strontium zinc silicate, a bioactive ceramic, in treating musculoskeletal disorders such as osteoporosis and sarcopenia in tail-suspended rats. The research highlights the role of Piezo1-mediated intracellular Ca²⁺ signaling in promoting osteogenesis and myogenesis, suggesting that targeting this pathway could serve as an effective therapeutic strategy for mechanical-related diseases. This approach may offer a universally applicable and efficient treatment option for such conditions.