Impact of Subclinical Hypothyroidism on Endocrine Features in Patients with Polycystic Ovary Syndrome

August 2025 in “ European journal of medical research ”

Rui Hua, Jingjun Li, Wei Yang, Yun Hua, Yulong Ma

subclinical hypothyroidism polycystic ovary syndrome thyroid-prolactin axis thyroid-stimulating hormone anti-Müllerian hormone gonadotropin PCOS TSH AMH

TLDR Subclinical hypothyroidism in women with PCOS affects thyroid and hormone interactions but not ovary structure.

Subclinical hypothyroidism in women with polycystic ovary syndrome (PCOS) is linked to changes in the thyroid-prolactin axis and a disrupted relationship between thyroid-stimulating hormone (TSH) and anti-Müllerian hormone (AMH). However, it does not seem to affect gonadotropin levels or ovarian morphology. Further prospective studies are needed to confirm these findings.

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Impact of Subclinical Hypothyroidism on Endocrine Features in Patients with Polycystic Ovary Syndrome

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