Extraction, Isolation, Characterization, and Biological Activity of Sulfated Polysaccharides Present in Ascidian Viscera Microcosmus Exasperatus

The study on Microcosmus exasperatus explores its sulfated polysaccharides, identifying three distinct types, including fucosylated-dermatan sulfate. These polysaccharides exhibit potential antitumor properties, reducing tumor cell viability and migration in mouse Lewis lung carcinoma cells, while showing significantly lower anticoagulant activity than standard heparin. The research suggests that M. exasperatus could be a sustainable source for therapeutic polysaccharides, with promising applications in cancer treatment. The study involved 3 replicates for each assay, indicating a need for further research to confirm these findings.