Synthesis of a 4-Azasteroid Hormones Compound

    January 2009 in “ Xiandai huagong ”
    Zang Hong-xia
    TLDR Finasteride was successfully synthesized from Pregnadienolone acetate.
    The document detailed a synthetic process for creating a 4-azasteroid hormone compound, specifically Finasteride. The synthesis involved multiple chemical reactions starting with Pregnadienolone acetate, which was transformed through a series of steps including oxidation, esterification, and ring closure. The final step involved dehydrogenation of the A-ring to produce Finasteride.
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