Effects of Taxifolin-3-O-Arabinopyranoside from Rhododendron Mucronulatum Root Extracts on the Alleviation of Hair-Loss Symptoms

The study explores the effects of taxifolin-3-O-arabinopyranoside from Rhododendron mucronulatum root extracts on hair-loss symptoms, focusing on inhibiting DHT production and preventing apoptosis in hair follicle cells. The compound showed concentration-dependent inhibition of DHT and apoptosis, increased IGF-1 expression, and decreased TGF-β1, indicating its potential as a treatment for male pattern hair loss. The study underscores the compound's antioxidant properties and suggests further exploration as a natural remedy for hair loss, although the number of participants was not specified.