The Use of New Hematological Markers in the Diagnosis of Alopecia Areata

    Gülhan Aksoy Saraç, Onur Acar, Tufan Nayır, Pinar Yildirim, Didem Dinçer Rota
    TLDR Certain blood markers, especially MLR, can help diagnose alopecia areata.
    This study investigated the use of hematological markers in diagnosing alopecia areata (AA) by comparing 70 patients with AA to 70 healthy controls. Results showed that hemoglobulin, monocyte, platelet, monocyte high-density lipoprotein cholesterol (MHR), monocyte lymphocyte ratio (MLR), and platelet lymphocyte ratio (PLR) were elevated in AA patients, while lymphocyte counts were lower. The study identified optimal cut-off values for these markers, with MLR, MHR, and PLR increasing the risk of AA by 6.3, 3.8, and 2.7 times, respectively. The findings suggest that MHR, PLR, and particularly MLR, can serve as significant diagnostic markers for AA.
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