Therapeutic Efficacy and Safety of Platelet-Rich Plasma for Hair Restoration: A Narrative Review

January 2026 in “ Journal of Cosmetics Dermatological Sciences and Applications ”

Kaindi Samuel Tumaini, Collins Daniel Pakaya, Jufang Zhang

platelet-rich plasma PRP androgenetic alopecia alopecia areata telogen effluvium erythema

TLDR PRP shows promise for hair restoration with mild side effects, but more research is needed for clear guidelines.

This narrative review assesses the efficacy and safety of platelet-rich plasma (PRP) for hair restoration, focusing on androgenetic alopecia, alopecia areata, and telogen effluvium. Analyzing 52 studies from 2020 to 2026, PRP showed promising results with response rates of 70%-86.7% for androgenetic alopecia, 56.7%-78.6% for alopecia areata, and 65%-75% for telogen effluvium. Adverse effects were mild, mainly injection-site pain and erythema, with high patient satisfaction. Despite these positive outcomes, variations in study design and treatment protocols hinder definitive conclusions, highlighting the need for further research to establish standardized guidelines.

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3 / 3 results

Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

research Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

July 2025 in “Clinical Cosmetic and Investigational Dermatology”

PRP therapy effectively improves hair density and reduces hair loss in androgenetic alopecia.

research A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia

1 citations , January 2022 in “Journal of Cutaneous and Aesthetic Surgery”

Combining 5% minoxidil with platelet-rich plasma is more effective for hair loss than minoxidil alone.

research Platelet-Rich Plasma in Alopecia Areata: Intradermal Injection Versus Topical Application with Transepidermal Delivery via Either Fractional Carbon Dioxide Laser or Microneedling

5 citations , January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)”

Injecting platelet-rich plasma or applying it with a laser or microneedling can treat hair loss effectively. The laser and microneedling methods cause less pain.