Comparative Efficacy of Topical Calcipotriol and Tacrolimus in Alopecia Areata: A Prospective Trial

This prospective trial compared the efficacy of topical calcipotriol and tacrolimus in treating alopecia areata. Conducted with 80 patients, divided into two groups of 40, the study found that topical calcipotriol (0.005%) was significantly more effective than tacrolimus (0.1%) in promoting hair growth over a 6-month period. Group A, treated with calcipotriol, showed a 67% efficacy rate, while Group B, treated with tacrolimus, had a 33% efficacy rate, with a statistically significant p-value of 0.0132. The study concludes that calcipotriol is superior to tacrolimus for hair growth in alopecia areata patients.