Efficacy of Topical Calcipotriol Betamethasone Dipropionate as a New Adjuvant Therapy to Follicular Unit Extraction Technique in Treatment of Stable Vitiligo: Clinical, Dermoscopic and Immunohistological Study

This study evaluated the efficacy of follicular unit extraction (FUE) alone and in combination with either topical calcipotriol betamethasone dipropionate (CBD) or NB-UVB phototherapy in treating stable nonsegmental vitiligo in 53 patients with 94 lesions. Group 2, which received FUE plus topical CBD, showed the best response in terms of repigmentation, color match, and size reduction, with significant results observed as early as the second week. The study concluded that FUE is an effective surgical treatment for stable vitiligo, and topical CBD successfully targets the immunological aspects of the condition. Dermoscopy was highlighted as a crucial tool for monitoring repigmentation.