Adjuvant Use of Topical Metformin With Standard Therapies in Recalcitrant Central Centrifugal Cicatricial Alopecia: A Case Series

January 2025 in “ JAAD Case Reports ”

Monica N. Williams, Janeth R. Campbell, Sach Thakker, Monique Chheda

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research Risk Factors and Comorbidities Associated With Central Centrifugal Cicatricial Alopecia

September 2023 in “International journal of women’s dermatology”

Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.

research Clinical Factors and Hair Care Practices Influencing Outcomes in Central Centrifugal Cicatricial Alopecia

May 2023 in “Archives of dermatological research”

Some factors like thyroid disease, diabetes treatment, hair dryers, natural hairstyles, and scalp conditions can affect the treatment results for a hair loss condition called CCCA.

research Beyond The Hot Comb: Updates In Epidemiology, Pathogenesis, And Treatment Of Central Centrifugal Cicatricial Alopecia From 2011 To 2021

16 citations , November 2022 in “American Journal of Clinical Dermatology”

research Central Centrifugal Cicatricial Alopecia

3 citations , April 2022 in “Cutis”

CCCA is a common, scarring hair loss in Black women that needs early detection.

research Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence

19 citations , May 2021 in “Clinical, Cosmetic and Investigational Dermatology”

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

research Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin

24 citations , January 2020 in “JAAD Case Reports”

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

research Fibrosing Alopecia in a Pattern Distribution

30 citations , January 2020 in “Journal of The American Academy of Dermatology”

Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.

research Association of Type 2 Diabetes With Central-Scalp Hair Loss in a Large Cohort Study of African American Women

16 citations , June 2019 in “International Journal of Women's Dermatology”

Type 2 diabetes may increase the risk of severe hair loss in African American women.

research Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia

25 citations , June 2018 in “Journal of The American Academy of Dermatology”

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.