Dynamic Transcriptome Profile Analysis of Mechanisms Related to Melanin Deposition in Chicken Muscle Development

This study investigates the genetic mechanisms behind melanin deposition in the pectoral muscles of Yugan black-boned chickens, which affects their economic value. By comparing differentially expressed genes (DEGs) between Yugan black-boned and Wenchang chickens at various embryonic stages, the study identified key genes involved in pigmentation, such as <i>EDNRB2</i>, <i>GPNMB</i>, <i>TRPM1</i>, <i>TYR</i>, and <i>DCT</i>. These genes were significantly associated with melanin biosynthesis and muscle pigmentation traits. The research highlights <i>MSTRG.720</i> as a potential candidate gene for melanin deposition, providing insights into the genetic regulation of muscle hyperpigmentation in black-boned chickens.