Trichoscopic Features, Clinical Correlates, and Risk Prediction in Female Pattern Hair Loss: A Retrospective Case-Control Study

This retrospective case-control study investigated the clinical and trichoscopic features of Female Pattern Hair Loss (FPHL) in 151 FPHL patients compared to 151 Chronic Telogen Effluvium (CTE) patients. The study found that a family history of androgenetic alopecia (AGA) and earlier onset of hair loss were more common in FPHL, indicating a genetic predisposition. Trichoscopic signs such as brown or white peripilar signs, white and yellow spot signs, and increased vellus hair were more prevalent in FPHL and correlated with disease severity. Independent risk factors for FPHL included a family history of AGA, acne, seborrheic dermatitis, menstrual disorders, a high-sugar and high-fat diet, poor sleep quality, and stress. A predictive nomogram model was developed, which could aid in optimizing FPHL management.