Method Development And Validation Of UV-Spectrophotometric Estimation Of Finasteride In Bulk And Pharmaceutical Dosage Form

A UV–Visible spectrophotometric method was developed and validated for estimating finasteride in bulk and pharmaceutical forms, useful for treating benign prostatic hyperplasia and androgenic alopecia. The method, using methanol and measuring absorbance at ~210 nm, showed excellent linearity (2–10 µg/mL, r² ≥ 0.999) and adhered to Beer–Lambert’s law. Validation followed ICH guidelines, confirming accuracy (98–102% recovery), precision (low %RSD <2%), and sensitivity with acceptable LOD and LOQ. This method is reliable, cost-effective, and suitable for routine quality control of finasteride formulations.