Management Strategies for Valproic Acid-Associated Alopecia

The document outlines a scoping review study aimed at identifying pharmacological management strategies for valproic acid (VPA)-associated alopecia. The study involves a comprehensive review of existing literature, with two independent reviewers screening titles and abstracts on the Covidence platform to identify relevant studies. The review includes only those studies that explicitly describe the management or treatment of VPA-induced alopecia, excluding those focused on other causes of alopecia or non-human subjects. The study employs a PRISMA-ScR flow diagram for data selection and uses univariate descriptive analyses to evaluate the data. The review aims to extract detailed information on study characteristics, demographics, VPA data, alopecia description, management strategies, and outcomes such as hair regrowth and treatment adherence.