Vitiligo

The special issue on vitiligo in Pigment International highlights significant advancements in understanding and treating vitiligo, recognizing it as a systemic disease rather than just a cosmetic concern. Recent research emphasizes the role of genetics, immunological pathways, oxidative stress, and the gut microbiome in vitiligo's pathogenesis. Phototherapy remains a cornerstone treatment, while new therapies like JAK inhibitors and topical Ruxolitinib show promise. Vitiligo patients have a reduced risk of skin and internal cancers, and emerging studies suggest a potential protective effect against Parkinson's disease and COVID-19. The issue underscores the importance of comprehensive management, including diet, exercise, and innovative medical and surgical treatments, to improve patient outcomes.