Transcriptome And Proteome Combined Analysis Of Wool Fiber Diameter Regulation Mechanism

September 2025 in “ Animal Bioscience ”

Lin Yue, Zengkui Lu, Tingting Guo, Bowen Chen, Jianbin Liu, Chao Yuan

TLDR Key genes and pathways affect wool fiber thickness, improving wool quality.

This study on fine-wool Alpine Merino sheep identified key microRNAs, circular RNAs, and pivotal genes involved in regulating wool fiber diameter through whole-transcriptome and proteome analyses. The research highlighted the significant role of triglyceride and energy metabolic pathways in influencing wool fiber diameter. These findings provide a theoretical basis for enhancing the wool industry's economic value by refining wool diameter and quality.

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