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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions

      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

    Research

    5 / 1000+ results

      research The Search for the Causes of Common Hyperandrogenism, 1965 to Circa 2015

      10 citations , March 2024 in “Endocrine Reviews”
      From 1965 to 2015, significant progress was made in understanding androgen excess disorders like premature adrenarche and polycystic ovary syndrome (PCOS). Key discoveries include the identification of unique plasma androgen patterns and the role of 11-oxytestosterones as major adrenal androgens. Research into PCOS pathogenesis highlighted areas such as neuroendocrinology, insulin resistance, and genetics, with genome-wide studies revealing the steroidogenic regulator DENND1A as a key factor. The DENND1A.V2 splice variant is overexpressed in PCOS theca cells, contributing to the PCOS phenotype. Obesity worsens PCOS symptoms through insulin resistance and increased testosterone production. Despite these advances, much remains to be understood about these disorders.
      Recent Advances in Oxasteroids Chemistry

      research Recent Advances in Oxasteroids Chemistry

      41 citations , March 2007 in “Steroids”
      New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

    Community Join

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      community Aggressive Hair Loss Journal For The Boys

      in Update  11 upvotes 1 year ago
      A 26-year-old male with a family history of early baldness documents his hair loss journey, using finasteride, dutasteride, and Nizoral, along with lifestyle changes like weightlifting and a vertical diet. Despite some stabilization, he continues to experience thinning and remains determined to fight hair loss.