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research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level

7 citations , August 2010 in “Medicinal Chemistry Research”

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases

51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

17 citations , June 2012 in “European journal of medicinal chemistry”

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

research Sulfatase inhibitors: a patent review

47 citations , November 2012 in “Expert Opinion on Therapeutic Patents”

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Steroid Sulfatase Inhibitors: Therapeutic Applications and Development

research Steroid sulfatase inhibitors

25 citations , May 2003 in “Expert Opinion on Therapeutic Patents”

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

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