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Development and Characterization of Poly(Lactic-Co-Glycolic Acid) Nanoparticles With Finasteride and In Vivo Evaluation of Their Efficacy in Hair Growth

research Development and characterization of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with finasteride and in vivo evaluation of their efficacy in hair growth

May 2024 in “Brazilian Journal of Hair Health”

Finasteride-loaded nanoparticles were successfully created for potential improved hair growth treatment.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

research Review: Topical Minoxidil for Male Pattern Baldness

25 citations , May 1986 in “The American Journal of the Medical Sciences”

Minoxidil helps hair growth and boosts self-esteem in balding men.

research Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products

8 citations , January 2011 in “Collection of Czechoslovak Chemical Communications”

Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.

research Characterization of the serotoninergic system in the C57BL/6 mouse skin

84 citations , July 2003 in “European journal of biochemistry”

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

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community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

in Finasteride/Dutasteride 247 upvotes 2 years ago

The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

community VDPHL-01 is Overrated and Ridiculous. This is just Oral Minoxidil.

in Research/Science 21 upvotes 1 year ago

VDPHL-01 is essentially a slow-release oral minoxidil, which is already known to work for hair growth. The formulation includes other ingredients like Medrogestone, Valproic acid, Setipiprant, and Cetirizine, but their effectiveness and necessity are questioned.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

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