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Did you mean 5-alpha-reductase inhibitor?

Glossary5-alpha-reductase inhibitor

blocks enzyme converting testosterone to dihydrotestosterone (DHT)

A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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Research

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research Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach

12 citations , November 2024 in “Plants”

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

research FRI-02 FROM GIRLS TO BOYS TO OLDER MEN, THE INTERESTING TALE OF THE GUEVEDOCES AND 5-ALPHA REDUCTASE INHIBITORS

March 2016 in “The Journal of Urology”

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

research Risk of Estrogen-Driven Malignancies in Females on 5-alpha Reductase Inhibitors

August 2024 in “Research Square (Research Square)”

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

research The risk of dementia with the use of 5 alpha reductase inhibitors

18 citations , June 2017 in “Journal of the neurological sciences”

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

research The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson’s disease

15 citations , January 2017 in “Experimental Neurology”

Finasteride reduces movement issues in Parkinson's disease rats.

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community Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid????

1 upvotes 8 years ago

The post discusses using a topical tincture containing zinc, azelaic acid, and other ingredients to inhibit 5 alpha-reductase activity for treating hair loss. The user plans to try this natural alternative before using finasteride or RU58841.

community Do these two supplements inhibit 5alpha-reductase?

in Chat 1 upvotes 5 years ago

Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.

community Me looking at my friends slight temple recession and calculating how long it'll take for him to bring it up to me, the Hairloss expert (I've been on finasteride for 6 months) so I can slap him with a 30 minute presentation about DHT miniaturization and 5-alpha reductase inhibitors

in Satire 536 upvotes 3 years ago

The post is a humorous take on the author's experience with hair loss and using finasteride for six months. The conversation includes discussions about hair loss, treatments like finasteride, and personal experiences with baldness.

community Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis?

in Finasteride/Dutasteride 6 years ago

The conversation is about determining which type of Saw Palmetto, either Chamaerops humilis or Serenoa repens, is effective for inhibiting the 5 alpha reductase enzyme related to hair loss. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.

community Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.

in Research/Science 9 upvotes 3 years ago

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

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