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5 / 801 resultslearn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
learn Fluridil
a topical anti-androgen with less systemic involvement
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn GT20029
research compound made to degrade androgen receptors in scalp
Research
5 / 1000+ results
research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia
Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands
Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
research 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance
DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
research Female pattern hair loss
Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
research Androgenetic alopecia; drug safety and therapeutic strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
Community Join
5 / 188 resultscommunity 7 months of Dutasteride 1mg daily and 2.5-5mg oral minoxidil daily on Diffused Unpatterned Alopecia
A user shared their 7-month progress using 1mg daily Dutasteride and 2.5-5mg daily oral Minoxidil for diffuse unpatterned alopecia, showing significant hair regrowth with reduced shedding and no side effects. They experienced a severe initial shed but now have visual improvement, despite hair still being thinner than before.
community Massive study on finasteride side effects released
The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.
community UPDATE - 7 months 2,5 dutatesteride
The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.
community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution
The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.
community One year anti androgen update CROWN
User used Finasteride, Dutasteride, and Minoxidil for one year to treat hair loss. They discussed possibly trying RU58841 or pyrilutamide in the future.