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Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract

22 citations , August 2009 in “Evidence-based Complementary and Alternative Medicine”

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride

research Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride

25 citations , September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology”

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

research Finasteride-induced depression: new insights into possible pathomechanisms

22 citations , December 2010 in “Journal of Cosmetic Dermatology”

Finasteride may increase depression by reducing brain cell growth.

In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride

research In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride

29 citations , January 1996 in “Journal of Pharmaceutical Sciences”

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

research Exploring the Potential of Eclipta alba: A Promising Approach for Hair Treatment Management through 5-Alpha Reductase Inhibition

June 2023 in “International journal of pharmaceutical quality assurance”

Eclipta alba extract could be a promising natural treatment for hair loss.

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community Has anyone here tried taking GLA supplements?

in Treatment 1 upvotes 1 year ago

GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

community 4.5 months on Finasteride 1mg a day, topical Minoxidil 5% twice a day, and ketoconazole shampoo 1% every time I shower.

in Progress Pictures 179 upvotes 2 years ago

The user is using finasteride, minoxidil, and ketoconazole shampoo for hair loss and stopped derma stamping to prepare for a future hair transplant. They are considering adding tretinoin to their treatment.

community Has anyone seen this study before? It claims that B6+Zinc can inhibit 5ar activity

in Technology 77 upvotes 3 years ago

The conversation discusses using B6 and Zinc to inhibit 5ar activity, similar to Fin and Dut. Minoxidil is mentioned as a supplementary treatment.

community Green tea/ soy Isoflavones supplements for MPB

in Product 4 upvotes 5 years ago

Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

community ~5 months topical minoxidil + oral finasteride results (swipe images). Slacked with minoxidil this past month, trying to wean off anyways. My last update because I’m hopping off fin and switching to RU in a few weeks (nothing to do with fin efficacy, just experimenting).

in Progress Pictures 145 upvotes 5 years ago

The user experienced significant hair thickening after using topical minoxidil and oral finasteride for about 5 months and is considering switching from finasteride to RU58841. Other users encourage the original poster to continue the current treatment due to the positive results.

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