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GlossaryAbiraterone

inhibits androgen production to treat prostate cancer

Abiraterone, also known as Zytiga, is a medication used primarily to treat prostate cancer. It works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) that can fuel the growth of prostate cancer cells. By reducing androgen levels, abiraterone helps to slow the progression of the disease.

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Research

5 / 89 results

research Abiraterone and spironolactone in prostate cancer: a combination to avoid

9 citations , November 2018 in “Acta Clinica Belgica”

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

research Revising the role of the androgen receptor in breast cancer

68 citations , April 2014 in “Journal of Molecular Endocrinology”

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases

51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Are sex discordant outcomes in COVID-19 related to sex hormones?

42 citations , June 2020 in “Seminars in Oncology”

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

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community Anyone know how to get second gen NSAA in the uk.

in Transgender 1 upvotes 10 months ago

A transwoman is struggling with hair loss despite using hormones, dutasteride, and Abiraterone, and is considering making her own treatments due to difficulty accessing them. She has also tried Eucapil and regularly uses Nizoral shampoo.

community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 2 years ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

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