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natural substance from Neem tree with medicinal and pesticidal properties
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Fluridil
a topical anti-androgen with less systemic involvement
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Research
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research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research Studies on the Disposition of Finasteride. (I). Absorption, Distribution and Excretion of (14C)finasteride after Single Oral or Intravenous Administration in Rats.
Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.
research The Interaction of Hair Fibers with Alkali Bromide Solutions
Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.
research Development of optimized self-nanoemulsifying lyophilized tablets (SNELTs) to improve finasteride clinical pharmacokinetic behavior
Improved tablets lead to faster, better drug absorption for hair loss treatment.
research Determination of Free Chemical Potential for Finasteride Diffusion through SDS Micelle Suggested as Alternative Living Membrane System
Finasteride diffuses spontaneously through SDS micelles, suggesting they can replace living cell membranes.
Community Join
5 / 1000+ resultscommunity People call companies stupid for making very high concentration Topical Fin solutions but I think they overlook the fact that the actual absorption rate of finasteride varies greatly
The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.
community Applying Minoxidil right after microneedling, is what I do now
The conversation discusses using Minoxidil and Finasteride for hair loss, with a focus on applying Minoxidil after microneedling to enhance absorption. There is also mention of considering oral Minoxidil due to potentially higher absorption rates.
community How long does it to start recovering from hair loss / thinning / super brittle after starting taking huge amounts of iron supplements?
Iron supplements can help improve hair thinning and brittle skin, but recovery time varies based on individual factors like ferritin levels and absorption rates. Regular blood tests are recommended to monitor ferritin and iron levels.
community Unexpected Serum DHT Elevation after Generic Dutasteride Use.
Switching from finasteride to a generic dutasteride led to unexpectedly high DHT levels, prompting a switch to a reputed brand and consideration of softgel capsules for better absorption. The user plans to retest DHT levels and may return to finasteride if issues persist.
community Rate My Routine: Oral Minoxidil 2.5mg daily, Topical Dutasteride (0.5ml, 1mg/ml) 2x weekly + DermaPen M8S 0.75mm, 18 pin 1x weekly, ketoconazole 2% shampoo 2x a week
A 28-year-old is experiencing early signs of balding and is using a routine that includes oral minoxidil, topical dutasteride, microneedling, and ketoconazole shampoo. They are seeking advice on the effectiveness of oral minoxidil with microneedling and the reliability of their product sources.