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    GlossaryAcetylcholinesterase (AChE)

    breaks down acetylcholine in the synaptic cleft

    Acetylcholinesterase (AChE) is an enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which is the space between nerve cells. This process is crucial for terminating nerve impulses and allowing muscles to relax after contraction. Inhibiting AChE can lead to prolonged muscle contraction and is a mechanism used by certain nerve agents and pesticides.

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      community 0.25mg Fin every day, 2 months status report

      in Finasteride/Dutasteride  9 upvotes 3 years ago
      A user reported increased shedding and some side effects like ball ache and potential watery semen after taking 0.25mg of finasteride daily for two months, but noted a high sex drive and considered the shedding a possible sign of new hair growth. Other users discussed dosage differences, with some suggesting starting with a smaller dose and monitoring effects, while others shared their experiences with no shedding or hair growth yet.

      community Minoxidil results in 3 months after stopping fin

      in Is this regrowth?  469 upvotes 1 year ago
      The user stopped finasteride due to testicular aches and switched to minoxidil, seeing positive results in three months. They are considering topical finasteride but are cautious because of past side effects from oral use.

      community Gyno caused by finasteride?

      in General  75 upvotes 9 months ago
      The user is experiencing chest sensitivity and muscle ache after using topical finasteride for a month and is concerned about potential gynecomastia. They are considering asking their doctor for blood work to check estrogen levels and are questioning whether to stop using finasteride.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 3 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Summaries of Finasteride Studies

      in Research/Science  20 upvotes 8 months ago
      Finasteride is effective in promoting hair growth and reversing hair miniaturization in men with androgenetic alopecia, with improvements seen in various studies over different durations. Some users report initial side effects like ball ache, which often resolve as the body adjusts.