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Research

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The Evolution of Healthy Skin to Acne Lesions: A Longitudinal, In Vivo Evaluation with Reflectance Confocal Microscopy and Optical Coherence Tomography

research The evolution of healthy skin to acne lesions: a longitudinal, in vivo evaluation with reflectance confocal microscopy and optical coherence tomography

19 citations , April 2019 in “Journal of the European Academy of Dermatology and Venereology”

Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.

research No evidence for follicular keratinocyte hyperproliferation in acne lesions as compared to autologous healthy hair follicles

7 citations , March 2018 in “Experimental Dermatology”

Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.

research 1318 Both lesional and non-lesional skin from acne patients shows robust IL-17-skewing and upregulation of antimicrobial peptides

April 2018 in “Journal of Investigative Dermatology”

Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.

research Acne inversa-like lesions associated with the multi-kinase inhibitor sorafenib

11 citations , December 2013 in “Clinical and Experimental Dermatology”

Sorafenib often causes skin side effects, indicating effective cancer treatment.

research Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin

45 citations , September 2000 in “Archives of dermatology”

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

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Community Join

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community I shaved my head. Trust the progress guys

in Shaved/buzzed 460 upvotes 1 year ago

The user shaved their head and is using finasteride and minoxidil for hair loss, expressing confidence in the process despite challenges. They are considering additional treatments like microneedling and are open to trying different looks, including facial hair growth.

community My 5 year hair loss journey on Min & Fin.

in Progress Pictures 1220 upvotes 3 months ago

A user shared their 5-year experience using minoxidil and finasteride, noting significant hair improvements without side effects. Consistency, a positive mindset, and lifestyle changes like a healthier diet and better sleep were key to their success.

community Boyfriend’s hair transformation in 10 months 🥲

in Progress Pictures 2281 upvotes 11 months ago

A boyfriend's hair improved significantly over 10 months using minoxidil, steroid cream, antihistamine cream, and wild growth oil, with a strict cleaning regimen. His partner's dedicated care contributed to the transformation.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What are these spots on my scalp

in Treatment 51 upvotes 2 years ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

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