August 2024 in “International Journal of Molecular Sciences” Actin filaments help root hairs grow faster and longer under low potassium stress.
1 citations
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September 2025 in “PLoS ONE” Actin and alpha-smooth muscle actin help skin heal in mouse fetuses.
20 citations
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June 2024 in “Journal of Autoimmunity” This study investigates the role of steroid metabolism in macrophages within rheumatoid arthritis (RA), revealing that inflammatory macrophages significantly increase the activation of glucocorticoids and androgens, which suppress inflammation. RNA-seq data from RA synovial macrophages showed changes in genes related to steroid metabolism, correlating with disease activity and pain. Key enzymes like 11β-HSD1, SRD5A1, and AKR1C3 were identified as crucial in this process, with 11β-HSD1 playing a novel role in androgen activation. The study highlights that increased glucocorticoid and androgen levels in macrophages and fibroblast-like synoviocytes help reduce inflammation. Additionally, the reduced presence of inactive steroid precursors in postmenopausal women may lead to higher disease incidence and severity.
January 2023 in “Methods in molecular biology” ROP GTPase helps control the growth of pollen tubes and root hairs by managing cell structure and movement.
11 citations
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January 1996 in “PubMed” Imaging living plant cells shows dynamic changes in actin and endoplasmic reticulum linked to root hair growth.