research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia 4 citations , July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
research Adam10 haploinsufficiency causes freckle-like macules in Hairless mice 13 citations , July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research ADAM17 variant causes hair loss via ubiquitin ligase TRIM47 mediated degradation May 2024 in “JCI insight” A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.
research Candidate genes of SARS-CoV-2 gender susceptibility 27 citations , November 2021 in “Scientific Reports” Men are more affected by COVID-19 due to differences in immune responses and protein expression.
research Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice 2 citations , June 2023 in “Journal of cell science” Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.