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Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.

After chemotherapy for early breast cancer, 33.4% of patients had long-term significant hair loss, with some hair regrowth over time, but treatments for hair loss were largely ineffective.

Docetaxel chemotherapy causes more long-term hair loss and dissatisfaction than paclitaxel.

Some early breast cancer patients have long-term hair loss after chemotherapy, especially older and postmenopausal women.

Chrysin makes docetaxel more effective and reduces its side effects in lung cancer treatment.