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research Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin

121 citations , June 2010 in “Australasian Journal of Dermatology”

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

research Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know?

111 citations , August 2015 in “Reviews in Endocrine and Metabolic Disorders”

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

research Adverse effects of voriconazole: Over a decade of use

100 citations , September 2016 in “Clinical transplantation/Clinical transplantation.”

Voriconazole can cause serious side effects, especially in long-term use.

research Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents

90 citations , May 2019 in “Drugs”

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

research Adverse effects of common medications on male fertility

77 citations , June 2015 in “Nature Reviews Urology”

Some common medications can harm male fertility, but many effects can be reversed.

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5 / 475 results

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

22 upvotes 8 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

in Minoxidil 73 upvotes 5 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 44 upvotes 5 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community Minoxadil 5% wv topical only? Experienced sides on 1mg fin and ~0.25mg fin. Solutions from here

in General 80 upvotes 1 year ago

The user experienced sexual side effects from finasteride and switched to using only topical minoxidil without side effects. They are seeking alternatives to finasteride, such as topical finasteride, to maintain hair without adverse effects.

community 5ARi of choice not working yet? Paper Review for efficacy + safety

in Research/Science 14 upvotes 5 months ago

Dutasteride is more effective than finasteride for hair loss, especially at the crown and midscalp, but both have similar side-effect profiles with low incidence of sexual adverse events. Improvement is measured visually, and significant results may take over 12 months to appear.

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