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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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learn Rapamycin
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
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learn Alopecia Areata
autoimmune disorder causing patchy hair loss
Research
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research Risk of age-related macular degeneration in men receiving 5α-reductase inhibitors: a population-based cohort study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
research Age-related differences in the reproductive and metabolic implications of polycystic ovarian syndrome: findings in an obese, United States population
Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
research Global sex disparities in lifetime risk of alopecia areata: a systematic analysis from the global burden of disease study, 1990 to 2021
Females have a higher lifetime risk of alopecia areata than males.
research Clinical perspectives on the age-related increase of immunosuppressive activity
Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
research HAIR AND SERUM TRACE ELEMENT AND MINERAL LEVELS IN PATIENTS WITH AGE-RELATED CATARACT
Low levels of zinc and selenium in the body are linked to a higher risk of cataracts.
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5 / 1000+ resultscommunity Massive study on finasteride side effects released
The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.
community Oral Min is much better than topical
Oral minoxidil is seen as more effective and convenient than topical minoxidil for hair regrowth, but it may cause heart-related risks. Users often combine it with finasteride or dutasteride, though some prefer topical treatments due to safety concerns.
community Should I risk changing to Dutasteride?
The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.
community "How can you have such nice hair when most people your age are balding"
A 22-year-old who had a hair transplant and is on medication has nice hair, which was complimented by their grandmother. Another person is 8 months post-transplant and taking dutasteride, oral minoxidil, and biotin but hasn't seen results yet.
community Age 18 vs Age 25, the importance of starting early
An 18-year-old began using Finasteride and Topical Minoxidil for hair loss, later switching to Oral Minoxidil and Dutasteride by age 25. The conversation emphasizes early treatment, potential side effects, and differing opinions on medication effectiveness.