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Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Global, Regional, and National Burden of Alopecia Areata in Children and Adolescents Aged 0-19 years from 1990 to 2021 and Projection to 2040
Alopecia areata cases in children are rising, especially in females and low-income regions, with a projected increase in China and decrease in the USA.
research Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels
Cases of alopecia areata and its impact on life quality rose globally, but when adjusted for age, the rates decreased, especially in poorer regions.
research Clinical Snippets
Skin has a larger surface area than thought, certain skin cells improve skin flap survival, better trials for skin conditions in children are needed, Stevens-Johnson syndrome rates vary by age and race, and better skin barrier function may reduce inflammation in the elderly.
research Epidemiological Transition and Forecasting of Diabetes Burden in Saudi Arabia: A Comprehensive Analysis From the Global Burden of Disease Study 1990–2023
Diabetes rates in Saudi Arabia are rising, especially Type 2, with more men affected, and will continue to increase by 2030.
research 412 DETECTION OF CIRCULATING PROSTATE CANCER CELLS BY MEANS OF AN ANTIBODY-CONJUGATED NANOPARTICULAR BIOSENSOR
The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.
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5 / 1000+ resultscommunity Microneedling + Min 2 months progress
The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.
community "Creatine causes hair loss" myth debunked once and for all
Creatine does not directly cause hair loss but may increase DHT levels, potentially worsening hair loss in those predisposed to male pattern baldness. Users have mixed experiences, with some reporting increased shedding and others seeing no effect.
community I am a dermatologist with a clinical interest in alopecia. AMA
In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
community UPDATE: The theory that explains everything. Please help me make this big!
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
community Switching from Finasteride to Dutasteride... probably
A 26-year-old male is considering switching from Finasteride to Dutasteride for more effective hair restoration, while others share experiences and advice on transitioning between these treatments. Many suggest gradually integrating Dutasteride with Finasteride to avoid shedding, and some report positive results with Dutasteride, though regrowth is not guaranteed.