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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 1000+ resultsresearch Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats
This review discusses the critical role of microRNAs (miRNAs) in regulating hair follicle development and cycling in cashmere goats, which are prized for their fine fiber. It highlights the influence of key miRNAs, such as miR-31, miR-22, and miR-214, on hair follicle morphogenesis, regeneration, and fiber traits. Recent advances in single-cell RNA sequencing and spatial transcriptomics have provided new insights into cellular heterogeneity and lineage specification. Integrative multi-omics approaches reveal complex regulatory networks involving miRNAs, while AI-driven analytics enhance biomarker discovery and therapeutic target identification. These findings inform breeding strategies to improve cashmere fiber quality and offer minimally invasive diagnostic tools for hair disorders. Future directions include improved miRNA delivery methods and AI-powered multi-omics approaches to advance hair follicle biology understanding and practical applications in medicine and agriculture.
research Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation
Combined oral minoxidil and finasteride significantly improve hair density in men with male pattern baldness.
research Drug Repurposing: Accelerating New Therapeutic Discoveries From Old Molecules (1990–2025)
Drug repurposing finds new uses for old drugs quickly and cheaply.
research Drug Repurposing: Accelerating New Therapeutic Discoveries from Old Molecules (1990–2025)
Repurposing existing drugs can quickly and cheaply find new treatments.
research Hair and Scalp Disease Detection Using Machine Learning and Image Processing
AI can accurately diagnose hair and scalp conditions and suggest treatments.
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5 / 502 resultscommunity Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!
This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.
community Common hair-loss drug consistently associated with higher rates of psychiatric harm
Finasteride and dutasteride can cause psychiatric side effects like depression and suicidal thoughts in some users, especially those with a history of mental health issues. While some users experience positive hair growth results, others face severe psychological effects, raising concerns about their safety and the need for careful monitoring.
community Recently went bald and will stop taking finasteride. Will stop taking it impact density in my beard and eyebrows? Also here’s after and before picture
The user recently went bald and plans to stop taking finasteride, questioning its impact on beard and eyebrow density. Responses suggest he looks good both bald and with thinning hair, with some recommending minoxidil for the crown and noting finasteride's effect on beard thickness.
community 2 months progress on minox 5% and .3% topical. Thoughts?
User shared 2-month progress using 6% minoxidil, seeing some regrowth. Others encouraged consistency and noted significant results typically appear around months 3-6.
community Cassiopea Announces Very Positive Interim Analysis Phase 2 Results for Breezula® (Clascoterone) in Treating Androgenetic Alopecia
Breezula® (Clascoterone) showed promising results in a Phase 2 trial for treating hair loss, being as effective as Propecia with no serious side effects. It might be released between 2021-2022, and a related acne treatment with the same active ingredient could be used in the meantime.