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Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

research Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions

14 citations , February 1998 in “Bioorganic & Medicinal Chemistry Letters”

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen

9 citations , January 2017 in “Organic Process Research & Development”

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

FeCl3-Catalyzed C-N Coupling Reaction Between Cyclic Ethers and Heterocyclic Amines

research FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines

4 citations , December 2014 in “European Journal of Chemistry”

Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.

research Kisspeptin and LH pulsatile temporal coupling in PCOS patients

49 citations , May 2018 in “Endocrine”

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

research Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

38 citations , July 2019 in “Nature Communications”

Par3 protein is essential for skin cell balance and stability.

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community Hair loss treatment tier list by Dr Oscar Muñoz

in Treatment 928 upvotes 1 year ago

Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

community Ashton Kutcher talked about on the tonight show how he was quitting dut. Looks like the Norwood reaper has already come to collect.

in Satire 623 upvotes 3 years ago

The conversation is about Ashton Kutcher's hairline and how some people think it looks good for his age, while others criticize it. Some mention that he used to use medication for hair loss but stopped.

community Tips/Advice on current situation aside from shaving bald

in Progress Pictures 1 upvotes 4 years ago

The user experienced worse hair after removing a wig system and has been using Hairband 82 Comfort Flex, Hair Max supplements, dermarolling, and a scalp massager for 4 months without clear results. They are hesitant to use Minoxidil due to shedding concerns and avoid finasteride due to side effects, preferring Saw Palmetto instead.

community Realistically is there anything else I can do aside from dut and oral min?

in Finasteride/Dutasteride 9 upvotes 1 year ago

Consider increasing dutasteride dosage to 2.5mg daily and continue using oral minoxidil. Check DHT levels, thyroid, vitamin D, and consider additional treatments like microneedling, RU58841, and improving diet and lifestyle.

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