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research The Mechanism of Androgen Actions in PCOS Etiology

30 citations , August 2019 in “Medical Sciences”

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

research Mechanism of action of androgen in hair follicles

25 citations , July 1994 in “Journal of dermatological science”

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

research Differences in the mechanisms of androgen action in hair follicles from women and men with androgenetic alopecia

2 citations , March 2000 in “CRC Press eBooks”

research Molecular mechanisms of androgen receptor functions

November 2007 in “Data Archiving and Networked Services (DANS)”

Androgen receptors play a key role in male development and prostate cancer, with treatments targeting androgen action.

research MECHANISM OF ACTION OF AVICENNIA MARINA HEARTWOOD EXTRACT AND AVICEQUINONE C ON HUMAN DERMAL PAPILLA CELLS ISOLATED FROM ANDROGENIC ALOPECIA PATIENTS

January 2016

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

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community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 2 years ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community Is it true that most hair loss treatments fall into one of two categories? If not, what am I missing?

in Treatment 4 upvotes 2 years ago

Hair loss treatments are generally categorized as anti-androgens, like finasteride and RU58841, which prevent hair loss by targeting DHT, and growth stimulators, such as minoxidil, rosemary oil, microneedling, and LLLT, which promote hair growth by increasing blood flow and growth factors. The user is seeking to confirm these categories and understand if there are other treatments or mechanisms of action.

community Can we have a thread that summarizes all treatments options in addition to the big 3 which we have some evidence for, their mechanism of action and whether they can be combined with the big 3(other than dermarolling)?

in Treatment 51 upvotes 8 years ago

The conversation discusses hair loss treatments beyond the commonly known three, focusing on separating effective treatments from myths. Dutasteride and low-dose oral Minoxidil are mentioned as having clinical evidence for increasing hair counts, but with potential side effects.

community Finasteride, Dutasteride, Pyrilutamide, RU58841 all accomplish the same thing in your body. Why skip around?

in Treatment 3 years ago

Hair loss treatments Finasteride, Dutasteride, Pyrilutamide, and RU58841 have different mechanisms of action. They can be used individually or stacked for better protection against hair loss.

community GT20029 and PP405 the new fin and min that we been waiting for ?

in Chat 36 upvotes 1 year ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

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