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a potent but unapproved and potentially problematic topical anti-androgen
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5 / 801 resultslearn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Stem Cell Factor
learn Overview
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
Research
5 / 1000+ resultsresearch Pre-receptor regulation of the androgen receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut
Gut bacteria can lower androgen levels in male mice.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Age‐dependent regulation by androgens of gene expression in the anterior hypothalamus and stress‐induced release of adrenal hormones in adolescent and adult male rats
Testosterone affects stress hormone levels differently in adolescent and adult male rats.
research Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes
The hHa7 gene is regulated by androgens in certain body hair, not scalp hair.
Community Join
5 / 1000+ resultscommunity Sebum production even on dutasteride, and its relation to MPB.
The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.
community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES
The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.
community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.
Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.
community Having androgen receptor density and sensitivity at wrong f*ing place
The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide
Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.