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research Weekly treatment with SAMiRNA targeting the androgen receptor ameliorates androgenetic alopecia

3 citations , January 2022 in “Scientific Reports”

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

research ISID1343 - Efficacy of asymmetric siRNA targeting androgen receptor for the treatment of androgenetic alopecia

May 2023

The conclusion is that a treatment called cp-asiAR can reduce hair loss and promote hair growth, making it a potential new therapy for androgenetic alopecia.

research 1343 Efficacy of asymmetric siRNA targeting androgen receptor for the treatment of androgenetic alopecia

April 2023 in “Journal of Investigative Dermatology”

cp-asiAR may effectively treat hair loss by targeting androgen receptors.

research Author Correction: Weekly treatment with SAMiRNA targeting the androgen receptor ameliorates androgenetic alopecia

April 2022 in “Scientific Reports”

Protac Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

research PROTAC Degraders of Androgen Receptor‐Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

December 2022 in “Small methods”

A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.

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community Is it true that most hair loss treatments fall into one of two categories? If not, what am I missing?

in Treatment 4 upvotes 2 years ago

Hair loss treatments are generally categorized as anti-androgens, like finasteride and RU58841, which prevent hair loss by targeting DHT, and growth stimulators, such as minoxidil, rosemary oil, microneedling, and LLLT, which promote hair growth by increasing blood flow and growth factors. The user is seeking to confirm these categories and understand if there are other treatments or mechanisms of action.

community Can GT20029's Become The Best Treatment Option?

in Chat 14 upvotes 3 years ago

The conversation discusses GT20029 as a potential hair loss treatment that could act like a cure by targeting androgen receptors in scalp hair follicles. Specific treatments mentioned include GT20029, with a user expressing hope that it could make male pattern baldness obsolete.

community What is preventing GT20029 from being the cure to androgenetic hair loss?

in Research/Science 9 upvotes 11 months ago

GT20029 is discussed as a potential treatment for androgenetic hair loss by targeting androgen receptors, unlike finasteride which reduces DHT broadly. Concerns include its effectiveness, genetic variations in androgen receptors, and availability, with some skepticism about its potential as a true alternative.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

in Research/Science 10 upvotes 8 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community GT20029: How It Works for Hair Loss - Hair Loss “Cure”

in Research/Science 33 upvotes 6 months ago

GT20029 is a potential treatment for androgenetic alopecia, addressing the root cause by targeting androgen receptors, unlike Minoxidil or Finasteride. It is seen as a preventative measure rather than a regrowth agent, with hopes for market release soon.

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