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GlossaryAntigen Presentation

process where immune cells display foreign substances to T-cells

Antigen presentation is a crucial process in the immune system where certain cells, called antigen-presenting cells (APCs), capture and display foreign substances (antigens) on their surface. This display helps T-cells recognize and respond to these antigens, initiating an immune response to fight off infections or diseases.

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T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus

research T-cell “induced-self” MHC class I/peptide complexes may enable “de novo” tolerance induction to neo-antigens occurring outside of the thymus

8 citations , October 2016 in “Experimental dermatology”

Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

research Skin Commensal Antigens: Taking the Road Less Traveled

February 2018 in “Trends in Immunology”

Skin bacteria can help wound healing by activating certain immune cells.

research A puzzling Presentation of Alopecia Areata: Sudden-Onset Whitening of Hair and its Spontaneous Resolution

July 2023 in “International Journal of Trichology”

The man's hair turned white suddenly but returned to normal on its own in 6 months.

research Quiescent Tissue Stem Cells Evade Immune Surveillance

169 citations , February 2018 in “Immunity”

Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.

research The Immune Functions of Keratinocytes in Skin Wound Healing

147 citations , November 2020 in “International Journal of Molecular Sciences”

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

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community When someone posts a scalp tension theory

in Satire 264 upvotes 5 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 3 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

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