research 129 Targeted inhibition of EGFR reduces anti-microbial defense mechanisms at the hair canal November 2023 in “Journal of Investigative Dermatology” Inhibiting EGFR weakens skin's defense against bacteria.
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta April 2018 in “Journal of Investigative Dermatology” Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development 69 citations , January 2021 in “Journal of Biological Chemistry” Plant-derived amino acids can help develop new antimicrobial drugs.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures 39 citations , October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research Expression of dermcidin in sebocytes supports a role for sebum in the constitutive innate defense of human skin 25 citations , November 2015 in “Journal of Dermatological Science” Sebum helps protect human skin from microbes.