research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
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5 / 1000+ resultsresearch Life threatening macrophage activation syndrome as the initial presentation of systemic lupus erythematosus: A case report and review of the literature
Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.
research Allosteric interactions prime androgen receptor dimerization and activation
Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Androgen receptor-mediated gene activation in prostate cancer cells
Androgen receptors help prostate cancer cells grow and resist drugs.
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5 / 679 resultscommunity My Theory Regarding a Cause and Cure for Androgenetic Alopecia
Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
community Glycine supplementaion is said to strongly upregulate 5-alpha Reductase (5-ar) Activity
Glycine supplementation may increase 5-alpha reductase activity, potentially affecting hair loss. Users discuss its impact on hair fall and its role in the body.
community Why does this industry still revolve around 5-AR inhibitors?
Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.
community Haircafe slams pp405 presentation. Are results really that bad?
PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.
community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?
Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.
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1 / 1 resultsExperts
4 / 4 results- 37
Hair Transplant SurgeonDr. Shashikiran AR, MD, MBBS, FRGHS
Mysuru, Karnataka, India
- 87Hair Loss Specialist
A.R. Kadam
Satara, Maharashtra, India
- 51
Hair Transplant SurgeonDr. Srigireesh A R, MBBS, MS, MCh, DrNB
Coimbatore, Tamil Nadu, India
- 40
DermatologistDr. Ahmad Haykal A.R.B, SpDVE, M.Kes, FINSDV, FAADV
Jakarta, Indonesia
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