research 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivo
17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
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5 / 1000+ resultsresearch Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
research NEONATAL INHIBITION OF ANDROGEN ACTIVITY ALTERS THE PROGRAMMING OF BODY WEIGHT AND OREXINERGIC PEPTIDES DIFFERENTIALLY IN MALE AND FEMALE RATS
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Early androgen activity after birth determines the hypothalamic expression of androgen and estrogen receptors in adulthood in female but not in male rats
Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
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5 / 322 resultscommunity Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects
Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.
community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?
User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.
community Aromatase Upregulation along with DHT down regulation could possibly hold the cure
The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.
community Can aromatase inhibitors make dutasteride/finasteride useless?
The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.
community Aromatise inhibitor for finasteride-estrogen side effects?
A user experienced mild side effects from 0.5mg finasteride daily, including increased estradiol and minor gynecomastia. They are considering taking a low dose of exemestane to reduce estrogen levels.
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