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research The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta?

65 citations , May 2006 in “Journal of Investigative Dermatology”

Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations , September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor

April 2019 in “Journal of the Endocrine Society”

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis

18 citations , August 2019 in “Clinical breast cancer”

Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.

research DHT and E2 synthesis-related proteins and receptors expression in male yak skin during different hair follicle stages

4 citations , August 2019 in “General and Comparative Endocrinology”

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

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community Minoxidil is able to suppress androgen receptors or increase aromatase effect. Blood test in pictures.

in Minoxidil 6 upvotes 3 years ago

A 24-year-old male experienced an increase in estradiol levels and symptoms like gynecomastia and excessive sweating after using Minoxidil for hair loss. His estradiol levels decreased after he stopped using Minoxidil.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 8 upvotes 5 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community Effect of melatonin on aromatase expression

in Update 5 upvotes 4 years ago

Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

community What happens if you combine dutasteride and a aromataze inhibitor?

in Question 4 upvotes 7 years ago

Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

community Theaflavin (Black Tea Extract) reduce DHT, androgen receptor activity and estrogen

in Research/Science 8 upvotes 3 years ago

Theaflavin, a black tea extract, may inhibit DHT and androgen receptor activity, but its effectiveness for hair loss is debated. Users report no significant improvement with theaflavin, while some find beta sitosterol helpful.

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