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GlossaryAtrophic Scars

sunken scars caused by tissue loss and collagen deficiency

Atrophic scars are a type of scar that appears sunken or depressed below the surface of the surrounding skin. They occur when the skin is unable to regenerate tissue, often due to conditions like acne, chickenpox, or trauma, leading to a loss of collagen and other structural components. These scars are characterized by their pitted appearance and can be challenging to treat, often requiring specialized dermatological procedures to improve their appearance.

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Research

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research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

62 citations , October 2017 in “JAMA facial plastic surgery”

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

research Potential genetic associations of acne scar phenotypes: IL1A in fibrotic scarring and CYB5R1 in atrophic scarring

April 2026 in “Biomedical Research and Therapy”

CYB5R1 and IL1A genes may be linked to different types of acne scars.

research Dermatoscopic Patterns in Keloid, Hypertrophic, and Atrophic Scars: Cross-Sectional Analysis and Clinical Correlation

October 2025 in “Dermatology Practical & Conceptual”

Dermatoscopy helps track scar changes and guide treatment.

research Updated Management of Atrophic Post Acne Scars: Review Article

October 2021 in “The Egyptian Journal of Hospital Medicine ”

Combination therapies work better than single treatments for atrophic acne scars.

research Multiple facial atrophic scars in childhood

February 2024 in “Pediatric Dermatology”

A 5-year-old girl with a rare genetic disorder, lipoid proteinosis, showed reduced new lesions but persistent scars after avoiding skin trauma.

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community Unofficial Dermapen/Roller Guide

in Treatment 254 upvotes 7 years ago

Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 6 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community Microneedling must reach the stem cells in the upper hair shaft

in Treatment 80 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

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