2 citations
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October 2025 in “Discover Immunity.” Alopecia Areata (AA) is an autoimmune hair follicle disease affecting up to 2% of the population, characterized by non-scarring hair loss. It results from the immune system mistakenly targeting hair follicles, disrupting their immune privilege. Diagnosis is based on clinical findings, dermoscopy, and histopathological methods. Genetic studies have linked susceptibility loci to hair follicle cycle signaling pathways, highlighting the disease's complexity. While no definitive treatment exists, current approaches aim to suppress the disease, and ongoing research into its immunological and molecular mechanisms may lead to new therapies.
11 citations
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June 2017 in “Mathematical Medicine and Biology A Journal of the IMA” The model helps understand and improve treatments for alopecia areata by simulating hair growth and immune cell interactions.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
23 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
286 citations
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August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.