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research The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances

4 citations , June 2025 in “Frontiers in Immunology”

BAFF-targeted therapies can reduce autoimmune disease activity, but more research is needed for precise treatments.

research Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss

July 2026 in “Nature Communications”

CXCR3+ T cells and B cells drive skin disease and hair loss in lupus, with potential targets identified for treatment.

research Vogt-Koyanagi-Harada disease occurring during pegylated interferon-α2b and ribavirin combination therapy for chronic hepatitis C

17 citations , January 2011 in “The Korean Journal of Hepatology”

Vogt-Koyanagi-Harada disease can develop during interferon therapy for chronic hepatitis C.

High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease

research High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease

17 citations , June 2016 in “Croatian Medical Journal”

Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.

Graft-Versus-Host Disease: Comprehensive Overview by the American Academy of Dermatology

research Graft-versus-host disease

58 citations , April 2012 in “Journal of the American Academy of Dermatology”

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

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Community Join

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Just started RU a month ago after being on fin and min for almost 3 years. Progress so far: My temples were pretty bare before this. Really hoping at least some of these become terminal.

in Is this regrowth? 391 upvotes 2 years ago

A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 3 years ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

in Research/Science 6 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Average r/bald user complaining

in Satire 398 upvotes 8 months ago

Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Beta Polypeptide

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Clinics

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Experts

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