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5 / 8 resultslearn Caffeine
the stimulant you know and love can be used topically to stimulate hair
learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
learn Epidermal Growth Factor
learn Thymosin Beta 4
Research
5 / 1000+ resultsresearch Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Consequences of Skin Barrier Dysfunction
A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid Omega-Hydroxylase Crucial to Acylceramide Production
Lack of a key enzyme causes severe skin issues and death in mice.
research Hidradenitis Suppurativa: A Folliculotropic Disease of Innate Immune Barrier Dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research Stratum Corneum Dysfunction in Dandruff
Improving skin barrier and using antifungal treatments can help manage dandruff.
research Hypothesis: Platelet-Rich Plasma as an Adjunct Therapy for Eczema Targeting Inflammation, Skin Barrier Repair, and Chronic Recurrence
The document hypothesizes that platelet-rich plasma (PRP) could be an effective adjunct therapy for eczema by addressing inflammation, repairing the skin barrier, and reducing chronic recurrence. Eczema involves immune dysregulation and barrier dysfunction, and current treatments often have side effects or limited efficacy. PRP, which contains growth factors and bioactive molecules, has shown promise in treating conditions like alopecia areata and psoriasis, which share similarities with eczema. Despite the lack of systematic studies on PRP for eczema, its safety profile and potential to modulate immune responses and enhance barrier function suggest it could be beneficial, warranting further clinical trials.
Community Join
5 / 251 resultscommunity Does seborrheic dermatitis block absorption of topicals?
User wonders if seborrheic dermatitis blocks absorption of topicals for hair loss. They use nizoral to improve the condition but it's not fully gone.
community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that
Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.
community After quitting min and fin I asked AI on how fix the mess I am in and it says:
Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.
community How is dht not beneficial to you?
DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.
community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone
Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.