Search

for
Search:

GlossaryB-cell lymphoma 2 (Bcl-2)

protein that inhibits cell death, often overexpressed in cancers

B-cell lymphoma 2 (Bcl-2) is a protein that helps regulate cell death (apoptosis) by inhibiting the process, allowing cells to survive longer than they should. This protein is often overexpressed in certain types of cancer, such as lymphomas, making it a target for cancer therapies aimed at restoring the normal process of cell death.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 1000+ results

Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

47 citations , April 2000 in “The American journal of pathology”

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

research A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

17 citations , January 2019 in “Journal of cancer”

The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.

research Effects of Diphencyprone on Expression of Bcl-2 Protein in Patients with Alopecia Areata

13 citations , January 2010 in “Immunopharmacology and immunotoxicology”

Diphencyprone increases Bcl-2 protein in patients with hair regrowth from alopecia areata.

research BCL-2 and Bax Expression in Skin Flaps Treated with Finasteride or Azelaic Acid

7 citations , January 2012 in “PubMed”

Azelaic acid and finasteride can help preserve skin flaps after surgery by increasing BCL-2 protein and decreasing bax protein.

research Expression of COX-2 and Bcl-2 in 50 Patients of Lichen Planus

April 2020 in “International journal of clinical and diagnostic pathology”

COX-2 and Bcl-2 proteins are involved in Lichen Planus.

View more "bcl-2" in research →

Community Join

3 / 3 results

community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

in Research/Science 4 upvotes 3 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

in Update 14 upvotes 4 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

community The end of balding: We may have just found the secret to hair regrowth

in Technology 680 upvotes 11 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.