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research Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research Case Report: Bi-allelic missense variant in the desmocollin 3 gene causes hypotrichosis and recurrent skin vesicles
A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research Author response: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
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5 / 1000+ resultscommunity ~3 months on Finasteride oral 1.25mg, and ~1.5 months of topical Minoxidil, with dermarolling & derma stamp bi weekly. 30 M. What are your guys thoughts?
A 30-year-old male using oral Finasteride, topical Minoxidil, and bi-weekly dermarolling has experienced noticeable hair regrowth, including new hairs at the hairline and temples, with reduced hair shedding. He reports no side effects from Finasteride after initial lethargy and mood changes.
community 4 years wearing hair systems - what nobody tells you when you start
Hair systems require frequent maintenance and can be costly, but a DIY approach with bi-weekly changes can help manage these issues. Minoxidil and finasteride were tried but not consistently used due to side effects and personal preferences.
community 10 month update - 1 mg oral fin
The user reports significant hair regrowth after 10 months using 1 mg oral finasteride daily and a 1.25 mm derma stamp bi-weekly with rosemary and jojoba oil. Other users commend the progress and inquire about the routine and side effects.
community One Year of Progress - 4/1/25 to 3/18/26
A 30-year-old shared their one-year hair regrowth progress using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, Nizoral shampoo, and bi-weekly microneedling. Users discussed the effectiveness of these treatments, with some noting shedding as a temporary phase before stronger regrowth.
community 3 and half years - Fin, Min — and some micro needling
A nearly 50-year-old male achieved significant hair regrowth and thickening over three years using daily finasteride, twice-daily topical minoxidil, and bi-weekly microneedling with a dermastamp. He experienced no side effects and found microneedling particularly effective for the crown area.