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GlossaryTemporal Hair Loss (Bitemporal Recession)

gradual hair thinning at the temples

Temporal hair loss, also known as temporal alopecia or thinning hair at the temples, refers to the gradual loss of hair in the temple regions of the scalp. This condition can be caused by various factors, including genetics, hormonal changes, stress, or certain medical conditions. It is often an early sign of androgenetic alopecia (male or female pattern baldness) and can be addressed through treatments like topical minoxidil, oral medications, or lifestyle changes.

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research Localized Trichorrhexis Nodosa Due to Compulsive Minoxidil Application

3 citations , January 2002 in “Actas Dermo-Sifiliográficas”

Excessive minoxidil use can damage hair structure.

research Frontal Fibrosing Alopecia in Postmenopausal Women

179 citations , December 2004 in “Journal of The American Academy of Dermatology”

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

research Telogen Effluvium: A Review

2 citations , January 2019 in “International Journal of Medicine in Developing Countries”

Telogen Effluvium is a common hair loss condition, particularly in women, with no specific FDA-approved treatment, and recovery can take up to 18 months.

research Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss

23 citations , January 2016 in “International Journal of Trichology”

Women with female pattern hair loss have lower Vitamin D3 levels.

research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq

8 citations , December 2017 in “Skin appendage disorders”

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

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community Kintor stealing pictures from a hair transplant clinic to promote their failed product (KX826, Pyrilutamide)

in Product 314 upvotes 1 year ago

Kintor is accused of using fake pictures to promote their product, Pyrilutamide (KX826), which failed Phase 3 trials. Users express disappointment and note similar false advertising has occurred with finasteride and minoxidil.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Should i be worried dut 6 months

in General 122 upvotes 5 days ago

The user has been using finasteride and minoxidil, then switched to dutasteride and minoxidil for six months without significant results, noticing thinning after increasing creatine dosage. They plan to consult a dermatologist to explore potential causes beyond androgenetic alopecia.

community PP405 2a study was a safety study. Some rational explaining.

in Research/Science 22 upvotes 4 months ago

The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.