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research 354 Investigating early molecular changes in a model of x-ray radiation-induced alopecia: spotlight on growth arrest and endothelial dysfunction

November 2025 in “Journal of Investigative Dermatology”

Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.

research Lean Women with Polycystic Ovary Syndrome

1 citations , February 2018 in “InTech eBooks”

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

research HtrA1L364P leads to cognitive dysfunction and vascular destruction through TGF‐β/Smad signaling pathway in CARASIL model mice

3 citations , July 2022 in “Brain and Behavior”

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

A Proposed Etiopathology of Persistent Dysfunctions Emerging from Use and Discontinuation of 5-Alpha Reductase Inhibitors: Sequelae of Drug-Mediated Microvasculopathy

research A proposed etiopathology of persistent dysfunctions emerging from use and discontinuation of 5-alpha reductase inhibitors: sequelae of drug-mediated microvasculopathy

February 2022

The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

research Metabolic and Vascular Inflammation in Alopecia Areata: Linking Uric Acid, Lipid Imbalance and ICAM ‐1 Upregulation

December 2025 in “Experimental Dermatology”

Improving blood vessel health and controlling uric acid may help manage alopecia areata.

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community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 638 upvotes 2 years ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community Control your blood pressure - for me this was my root issue

in Treatment 9 upvotes 1 year ago

Managing blood pressure can help with hair loss, as seen with the use of medications like Cialis and oral minoxidil, which improved hairline and blood pressure. Lifestyle changes, such as reducing stimulant use and adjusting testosterone replacement therapy (TRT) doses, also play a role in addressing hair loss and overall health.

community A Different Take on Curing MBP

17 upvotes 7 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 316 upvotes 1 year ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community So depressed and upset with how much progress I’ve lost

in Chat 51 upvotes 3 years ago

A 20-year-old started taking finasteride for hair loss at 18, saw improvement, but developed erectile dysfunction (ED) after taking accutane. Despite stopping both medications, ED persisted, and hair loss worsened. Advice given includes considering tadalafil for ED, resuming finasteride, using minoxidil, and addressing psychological factors through positive thinking and lifestyle changes.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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